Invasive Prenatal (Fetal) Diagnostic Testing

Single-Gene Disorders Invasive diagnostic prenatal (fetal) testing for molecular analysis for single-gene disorders may be considered medically necessary when a pregnancy has been identified as being at high risk: 1. For autosomal dominant conditions, at least 1 of the parents has a known pathogenic mutation. 2. For autosomal recessive conditions: a. Both parents are suspected to be carriers or are known to be carriers, OR b. One parent is clinically affected and the other parent is suspected to be or is a known carrier. 3. For X-linked conditions: A parent is suspected to be or is a known carrier.